Prognosis of gastric cancer with liver metastases after simultaneous primary tumor and liver resections

نویسندگان

  • Jianguo Zhou
  • Dongbing Zhao
  • Jianjun Zhao
  • Jianqiang Cai
چکیده

Objective: To investigate the prognostic factors of gastric cancer with liver metastases after simultaneous primary tumor and liver resections. Methods: The clinical data of 21 gastric cancer cases with liver metastases that were treated with simultaneous primary tumor and liver resections during the period of February 1999 to December 2010 were retrospectively analyzed. Results: The in-hospital mortality was 0%, the 1-year cumulative survival rate for gastric cancer patients with liver metastases that were treated with simultaneous primary tumor and liver resections was 71.4%, the 3-year cumulative survival rate was 22.2%, and the 5-year survival rate was 14.8%. Univariate analysis showed that an intravascular tumor embolus (P = 0.002), N stage (P = 0.010), and D2 resection (P = 0.014) were prognostic factors of gastric cancer with liver metastases after simultaneous primary tumor and liver resections. Multivariate analysis showed that N stage (P = 0.001), the distribution of metastatic lesions (P = 0.032), and D2 resection (P = 0.037) were independent prognostic factors. Conclusion: Simultaneous primary tumor and liver resections for the treatment of gastric cancer with liver metastases was safe, and selective surgical treatment can improve the prognosis.

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تاریخ انتشار 2016